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Comedomed+ Intensive Anti-Blemish Care.

Cleanance Comedomed+ Intensive Anti-Blemish Care, targets pimples, blackheads and marks at their root, with a 1-year* anti-relapse efficacy.

Cleanance

COMEDOMED Anti-blemishes Concentrate

Permanent

  • 1 year without recurrence of blemishes**
  • Anti-blemishes, Anti-recurrence, Excellent tolerance.
  • Pregnant women, Young mothers, Teenagers, Adults
  • prod1
    Dermatologically tested
    • COMEDOMED Anti-blemishes Concentrate
    • COMEDOMED Anti-blemishes Concentrate
    • COMEDOMED Anti-blemishes Concentrate

      Cleanance

      COMEDOMED Anti-blemishes Concentrate

      Permanent Reduces imperfections - Tightens pores - Reduces excess sebum

      Cleanance Comedomed anti-blemishes concentrate reduces the appearance of spots and blackheads and limits their recurrence*. Prescribed by dermatologists**.

      • 1 year without recurrence of blemishes**
      • Anti-blemishes, Anti-recurrence, Excellent tolerance.

      Usable by Pregnant women - Young mothers - Teenagers - Adults

      Age From 12 year(s)

      Skin type Acne-prone skin

      Need Anti-imperfections - Anti recurrence

      Made in France

      Cleanance Comedomed concentrate reduces the appearance of spots and blackheads from seven days***. Thanks to the unique mode of action of Comedoclastin™, a plant-based active ingredient with patented properties****, it fights blemishes at the root, targeting micro-comedones, and ensures anti-recurrence action*.
      Tested on more than 4,600 subjects and prescribed by dermatologists**, Cleanance Comedomed concentrate is the expert care for all acne-prone skin types in teenagers from the age of 12 and adults (including pregnant women).
      Apply twice a day (morning and evening) to the face, torso and back. Its light texture with a non-greasy finish leaves the skin matte.

      A few words from our expert

      The anti-blemishes concentrate acts on the microcomedones at the root of blemishes in acne-prone skin for long-lasting efficacy, without recurrence.

      Benefit

      Anti-blemishes concentrate that reduces the appearance of spots from 7 days*** and prevents their recurrence for 1 year*****, prescribed by dermatologists**.

      Benefits

      • EFFECTIVE on all types of imperfections on acne-prone skin. Tested on over 4600 subjects.
      • FAST : reduces pimples in just seven days***. Prevents recurrence for one year*****.
      • EXCELLENT TOLERANCE for all skin types, even the most sensitive. Prescribed by dermatologists**.

      Product scent

      Fragrance-free

      Packaging that does not contain recycled material
      Fully recyclable packaging

      19/7/2026

      *Used twice a day on the face, it helps limit the reappearance of blemishes. Efficacy demonstrated over 8 weeks, 37 subjects.
      **IQVIA - Xponent PharmaOne - Acne market (83A1A) in pharmacies in France - Year 2021 - volume & value.

      *Used twice a day on the face, it helps limit the reappearance of blemishes. Efficacy demonstrated over 8 weeks, 37 subjects.
      **IQVIA- Xponent PharmaOne - acne market (83A1A) in pharmacies in France - Year 2021 - volume & value.
      ***Clinical scoring, twice a day on the face, 51 subjects.
      ****Patent pending.

      **IQVIA - Xponent PharmaOne - Acne market (83A1A) in pharmacies in France - Year 2021 - volume & value.
      ***Clinical scoring, twice a day on the face, 51 subjects.
      *****International observational clinical study, 85% of patients without acne relapse at 1 year (according to the GEA >3 protocol definition of relapse requiring the introduction of a medicinal treatment – oral or local), 54 subjects, 2 applications per day of Cleanance Comedomed for 1 year.

      **IQVIA - Xponent PharmaOne - Acne market (83A1A) in pharmacies in France - Year 2021 - volume & value.
      ***Clinical scoring, twice a day on the face, 51 subjects.
      *****International observational clinical study, 85% of patients without acne relapse at 1 year (according to the definition of relapse in the GEA >3 protocol requiring the introduction of a medicinal treatment - oral or local), 54 subjects, 2 applications per day of Cleanance Comedomed for 1 year.

      Application

      Frequency of use

      2 times a day

      Comedomed can be used alone, in combination with, or after a medicinal acne treatment.
      It can be applied on cleaned face, torso and back, morning and evening.
      Expert Tip :
      A piece of advice : keep your routine short but essential !
      • 1 thorough facial cleansing or make-up removal : morning and evening !
      • 1 anti-blemishes care : also morning and evening.

      Ingredients

      AVENE THERMAL SPRING WATER (AVENE AQUA). ISOPROPYL ALCOHOL. PEG-6. GLYCERIN. SILYBUM MARIANUM FRUIT EXTRACT. SILICA. POLYACRYLATE-13. POLYISOBUTENE. POLYSORBATE 20. SORBITAN ISOSTEARATE. WATER (AQUA)

      The consumer is advised to systematically check the composition of the product before purchasing it.

      Comedoclastin™

      Comedoclastin™

      Plant-based active ingredient with patented properties from Pierre Fabre Research. Milk thistle extract acts on epithelial cells reducing the formation of micro-comedones and preventing new spots.
      Avene-thermal-water

      Avene thermal water

      Thanks to a unique mineral and biological signature, it is known for soothing, strengthening and rebalancing the skin.

      Results

      • Reduces spots within 7 days¹
      • 1 year without recurrence for 85% of users²
      • Reduces the appearance of blemishes by 45% from 2 months³

        ¹Cotation clinique, 2 fois/jour sur le visage, 51 sujets.
        ²International observational clinical study, 85% of patients without acne relapse at 1 year (according to the GEA >3 protocol definition of relapse requiring the introduction of a medicinal treatment – oral or local), 54 subjects, 2 applications per day of Cleanance Comedomed for 1 year.
        ³Comparative clinical study (Traited group twice by day group N=18), control group (N=18) for 56 days. 36 subjects with mild to moderate imperfections.
        Results COMEDOMED Anti-blemishes Concentrate
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